Lokeswara Rao Sajja, MS., MCh, FACS (USA)

Personal Allusion

I am humbled to be a Senior Consultant Cardiac Surgeon in the Department of Cardiothoracic Surgery at STAR Hospitals, Hyderabad, India. Throughout my academic career, I have been lucky enough to train with the giants of coronary artery bypass surgery. While bypass surgery may appear as one of the more basic cardiac operation, the complexities of the patient and the variations of the operation require exquisite attention to detail to keep patients safe, which is my main priority. With the support of the incredible staff, including the cardiac anesthesia team, nurses, technicians and surgeons, I have the utmost confidence that I am in the best possible environment to provide the highest level of care to my patients.

Specialties and Expertise

Specialties

  • Adult Cardiac Surgery
  • Coronary Bypass Surgery
  • Cardiac Surgery
  • Valvular Heart Surgery

Expertise

  • Coronary Bypass Surgery
  • On-pump and off-pump CABG.
  • Multiple arterial grafting (Internal mammary arteries, radial artery grafts)
  • Redo Cardiac bypass surgery
  • Cardiac Bypass Surgery
  • Open Heart Surgery
  • Aortic Aneurysm Surgery
  • Repair Aortic Dissection and Aneurysm
  • Minimally Invasive Cardiac Surgery
  • Repair of Cardiac Aneurysm
  • Mitral valve surgery (repair/replacement).
  • Aortic valve replacement.
  • Aortic and Mitral Valve Surgery
  • Aneurysmectomy of Heart (left ventricle)
  • Aortic Stent Graft
  • Surgical Repair of Aortic Dissection
  • Aortic Aneurysm Repair
  • Surgery of Ascending Aortic Aneurysm
  • Aortic Arch Surgery
  • Repair of Thoracic Aortic Aneurysm

Biography

Dr. Lokeswara Rao Sajja is a Senior Consultant Cardiothoracic Surgeon and In-charge of Academics, Director of Cardiovascular Research at STAR Hospitals, Hyderabad, India.

Dr. Sajja completed his undergraduate studies and earned his medical degree in Guntur, India at the Guntur Medical College. He subsequently completed his MS at the JIPMER, Pondicherry, and also completed his super-specialization in Cardiothoracic and Vascular Surgery at the AIIMS, New Delhi.   He obtained advanced training under world-renowned Cardiac Surgeon, Prof. Denton A. Cooley at the Texas Heart Institute, Houston, Texas, USA.

In addition to his clinical expertise, Dr. Sajja is currently the In-charge of Academics and Director of Research in the Department of Cardiothoracic Surgery. Throughout his academic career, Dr. Sajja has authored more than 75 peer-reviewed journal articles. He was the lead investigator of an Indian, multi-centric randomized, controlled trial, the first multi-centric RCT in Cardiac Surgery in India, which aimed to determine the optimal strategy for coronary artery bypass surgery (the PROMOTE Patency Trial). He also conducted mono-centric RCT in Cardiac Surgery to determine the optimal strategy for CABG in patients with renal insufficiency.  He is also an Investigator in Arterial Revascularization Trial, the largest multi-national RCT in Cardiac Surgery, lead center at Oxford. He has given expert presentations at national and international meetings to share his knowledge of coronary artery bypass surgery and the use of multiple arterial grafts. He currently serves as the President of the Society of Coronary Surgeons and also as the Vice-President of the Indian Association of Cardiovascular-Thoracic Surgeons.

Dr. Sajja's interests include all aspects of adult cardiac surgery. Along with his expert training and knowledge in coronary artery bypass surgery, including the use of multiple arterial grafting (radial artery conduits, the use of bilateral internal mammary arteries), Dr. Sajja also specializes in structural heart disease, valvular dysfunction, and complex aortic procedures. He designed a mechanical prosthetic valve that does not require long-term anticoagulation, for which he was granted patency by the United States Patent and Trademark Office.

As a Chairman of Sajja Heart Foundation, Dr. Sajja oversees ongoing clinical trials and provides strategic growth plans to increase investigator-initiated trials, pragmatic trials, and ongoing improvements and enhancements to the existing clinical trial infrastructure.

Clinical Trials Experience

(i)            He is a keen researcher and a master clinical trialist in Cardiac Surgery. He conducted India's first multicentre Randomized Control Trial (RCT) in Cardiac Surgery (PROMOTE Patency Trial).

(ii)         He has represented India as a Site Principal / Co- Investigator in multinational clinical Trials in Cardiac Surgery (Arterial Revascularization Trial, ROMA Trial).

Coronary Artery Bypass Graft (CABG)
 

Increased prevalence of CAD in India has led to an increase in number of coronary artery bypass grafting. CABG accounts for more than 60% of all cardiac operations and every year more than 1, 50,000 coronary bypass operations are being carried out in India.

The STAR Hospitals Department of Cardiothoracic Surgery has long history of performing coronary artery bypass surgery; the most commonly performed surgical procedure for treating multi-vessel coronary artery disease.  The mortality rate among these patients was less than 1%.  Our outcomes are consistently among the best in India, and routinely exceed national average and match the best centers in the US.

The coronary artery disease affects many of the younger individuals at the prime of their productive life, about a decade earlier than our western counterparts. The most common surgical treatment for coronary artery disease is coronary artery bypass graft (CABG). This procedure has proven to lower the risk of future heart attack and the need for additional procedures. It has also proven to result in a longer life expectancy.

 

Dr. Sajja's publications

1. Talukder S, Dimagli A, Benedetto U, et al and on behalf of the ART Investigators, Prognostic factors of 10-year mortality after coronary artery bypass graft surgery: a secondary analysis of the arterial revascularization trial, Eur J of Cardio-Thorac Surg, 2022; ezac043

2. Taggart DP, Gaudino M, Gerry S, et al and on behalf of the ART Investigators. Effect of total arterial grafting in the Arterial Revascularization Trial, J Thorac Cardiovasc Surg ,2022;163: 1002-1009.e6,

3. Yadava, O.P., Narayan, P., Padmanabhan, C. et al. IACTS position statement on “2021 ACC/AHA/SCAI Guideline for Coronary Artery Revascularization”: section 7.1—a consensus document. Indian J Thorac Cardiovasc Surg 2022; 38, 126–133.

4. Gaudino M, Audisio K, Rahouma M, et al. and on behalf of the ART Investigators. Comparison of Long-term Clinical Outcomes of Skeletonized vs Pedicled Internal Thoracic Artery Harvesting Techniques in the Arterial Revascularization Trial. JAMA Cardiol. 2021; 6:1380–1386

5. Taggart DP, Gaudino M, Gerry S, Gray A, Lees B, Sajja LR, Zamvar V, Flather M, Benedetto U, and on behalf of the ART Investigators Ten-year outcomes after off-pump versus on-pump coronary artery bypass grafting: Insights from the Arterial Revascularization Trial. J Thorac Cardiovasc Surg ,2021; 162,591-599.e8,

6. Gaudino M, Audisio K, Rahouma M, et al and on behalf of the ART Investigators Association between sternal wound complications and 10-year mortality following coronary artery bypass grafting,The Journal of Thoracic and Cardiovascular Surgery,2021 S0022-5223(21)01812-2

7. Sajja LR. Prediction of perioperative mortality in cardiac surgery – Risk scoring systems: In quest of the holy grail. J Indian Coll Cardiol 2021; 11:41-3

8. Sajja LR. A narrative review of redo coronary artery bypass grafting. AME Med J 2020; 6:20.

9. Benedetto U, Gaudino MF, Dimagli A, Gerry S, Gray A, Lees B, Flather M, Taggart DP, ART Investigators. Postoperative Atrial Fibrillation and Long-Term Risk of Stroke After Isolated Coronary Artery Bypass Graft Surgery Circulation 2020;142: 1320-1329

10. Sajja LR, Sarkar K, Mannam G. et al One-year outcomes of off- and on-pump coronary artery bypass grafting: PROMOTE patency trial 2020;36:469-475.

11. Sajja, L.R., Sarkar, K., Mannam, G. et al. Graft patency at 3 months after off- and on-pump coronary bypass surgery: a randomized trial. Indian J Thorac Cardiovasc Surg 2019; 36:93-104.

12. Sajja, L.R., Singh, S., Mannam, G. et al. Impact of occult renal disease on the outcomes of off- pump and on-pump coronary artery bypass grafting Indian J Thorac Cardiovasc Surg 2019;35:150-157.

13. Taggart DP, Benedetto U, Gerry S, Altman DG, Gray AM, Lees B, Gaudino M, Zamvar V, Bochenek A, Buxton B, Choong C, Clark S, Deja M, Desai J, Hasan R, Jasinski M, O'Keefe P, Moraes F, Pepper J, Seevanayagam S, Sudarshan C, Trivedi U, Wos S, Puskas J, Flather M; Arterial Revascularization Trial Investigators. Bilateral versus Single Internal-Thoracic-Artery Grafts at 10 Years. N Engl J Med. 2019; 380:437-446

14. Yadava OP, Sajja L. Coronary: at par with rest of the world. Section 10: cardiac Surgery in India. In CSI textbook of Cardiology. The Indian Perspective, 2018.pp 576-590. Ed. Deb P K. Jay Pee Brothers, New Delhi.

15. Mitra K. Nadim, Lui G. Forni, Azra Bihorac, Charles Hobson, Jay L.   Koyner, Andrew Shaw, George    J.    Arnaoutakis, Xiaoqiang    Ding, Daniel     T.    Engelman, Hrvoje Gasparovic, Vladimir Gasparovic, Charles A. Herzog, Kianoush Kashani, Nevin Katz, Kathleen D. Liu, Ravindra L. Mehta, Marlies  Ostermann, Neesh   Pannu, Peter  Pickkers, Susanna Price, Zaccaria Ricci, Jeffrey B. Rich, Lokeswara R. Sajja, Fred A. Weaver, Alexander Zarbock, Claudio Ronco, John A. Kellum. Cardiac and Vascular Surgery–Associated Acute Kidney Injury: The 20th International ConsensusConference of the ADQI (Acute Disease Quality Initiative) Group Journal of the American Heart Association. 2018;7:e008834

16. Benedetto U, Douglas G Altman, Flather M, Gerry S, Gray A, Lees B, Taggart DP. On behalf of the Arterial revascularization trial investigators. Incidence and clinical implications of intraoperative bilateral internal thoracic artery graft conversion: Insights from the Arterial Revascularization Trial. J Thorac Cardiovasc Surg 2018; 155:2346-2355.

17. Umberto Benedetto, Douglas G.Altman, Stephen Gerry, Alastair Gray, Belinda Lees , Marcus Flather , David PTaggart MD,on behalf of the Arterial Revascularization Trial investigators. Off- pump versus on-pump coronary artery bypass grafting: Insights from the Arterial Revascularization Trial. J Thorac Cardiovasc Surg 2018;155: 1545-1553.e7

18. Umberto Benedetto, Douglas G. Altman, Stephen Gerry, Alastair Gray, Belinda Lees, Gianni D. Angelini, Marcus Flather, David P. Taggart, on behalf of the ART (Arterial Revascularization Trial) Investigators. Safety of Perioperative Aprotinin Administration During Isolated Coronary Artery Bypass Graft Surgery: Insights from the ART (Arterial Revascularization Trial) J Am Heart Assoc 2018;7: e007570. DOI: 10.1161/JAHA.117.007570

19. Taggart DP, Altman DG, Flather M, Gerry S, Gray A, Lees B, Benedetto U, Arterial Revascularization Trial Investigators. Associations Between Adding a Radial Artery Graft to Single and Bilateral Internal Thoracic Artery Grafts and Outcomes Insights From the Arterial Revascularization Trial. Circulation 2017;136: 454–463.

20. Sajja LR, Beri P. Bilateral internal thoracic artery grafting in India —Time to raise the bar. Ind Heart J. 2017; 69: 640-645.

21. Benedetto U, Altman DG, Gerry S, Gray A, Lees B, Flather M, Taggart DP, on behalf of the ART Investigators, Impact of dual antiplatelet therapy after coronary artery bypass surgery on 1-year outcomes in the Arterial Revascularization Trial. Eur J Cardio-Thorac Surg 2017; 52:456–461.

22. Taggart DP, Altman DG, Gray AM , Lees B, Gerry S, Benedetto U, Flather M, , for the ART Investigators. Randomized trial of bilateral versus single internal-thoracic-artery grafts. N Engl J Med 2016;375:2540-9.

23. Benedetto U, Altman DG, Gerry S, Gray A, Lees B, Pawlaczyk R, Flather M, Taggart DP; Arterial Revascularization Trial investigators. Pedicled and skeletonized single and bilateral internal thoracic artery grafts and the incidence of sternal wound complications: Insights from the Arterial Revascularization Trial. J Thorac Cardiovasc Surg. 2016 ;152:270-6.

24. Sajja LR, Strategies to reduce deep sternal wound infection after bilateral internal mammary artery grafting. Int J Surg. 2015; 16: 171-178.

25. Sajja LR, Mannam G. Internal thoracic artery: anatomical and biological characteristics revisited. Asian Cardiovascular & Thoracic Annals.2015; 23:88-99.

26. Sajja LR, “The Journey of Surgery for Coronary Artery Disease in India: Adoption, Customization and Innovation”. Sadasivan Oration. Indian J Thorac Cardiovasc Surg. 2014; 30:116-128.

27. David P. Taggart, Douglas G. Altman, Alastair M. Gray, Belinda Lees, Fiona Nugara, Ly-Mee Yu, Marcus Flather, on behalf of the ART Investigators, Effects of on-pump and off-pump surgery in the Arterial Revascularization Trial. Eur J Cardio-Thorac Surg 2015; 47: 1059–1065.

28. Sajja LR, Mannam G. Reduction of Sternal Infection in Off-pump CABG by Modified Pedicle Harvesting (Correspondence). Ann Thorac Surg 2013; 96:2283–90.

29. Sajja L R, Mannam G C, Dandu SBR, Sompalli S. Reduction of sternal wound infections in diabetic patients undergoing off pump coronary artery bypass surgery and using modified pedicle bilateral internal thoracic artery harvest technique. J Thorac Cardiovasc Surg; 2012;144:480-485.

30. Sajja LR and Mannam G. The less blood product the less renal impairment? Ann Thorac Surg 2012; 94:332-333.

31. Sajja L R, Mannam G C, Chakravarthi R.M, Guttikonda J, Sompalli S, Bloomstone J. Impact of preoperative renal dysfunction on outcomes of off-pump coronary artery bypass grafting. Ann ThoracSurg 2011; 92: 2161-2167.

32. Taggart DP, Altman DG, Gray AM, Lees B, Nugara F, Yu LM, Campbell H, Flather M; ART Investigators. Randomized trial to compare bilateral vs. single internal mammary coronary artery bypass grafting: 1-year results of the Arterial Revascularisation Trial (ART). Eur Heart J. 2010; 31:2470-81.

33. Sajja LR, Mannam GC. Nonobstructive ectopic accessory mitral valve tissue in association with left ventricular apical aneurysm. J Thorac CardiovascSurg 2010; 139:218-220.

34. Sajja LR, Mannam GC. Mitral valve repair for chronic ischemic mitral regurgitation: A review. Valves & Chambers, The Journal of Cardiology 2009;1:1-10.

35. Sajja LR, Mannam GC, Dandu SBR, Pathuri SN, Saikiran KVSS, Sompalli S. Outcomes of mitral valve repair for chronic ischemic mitral regurgitation. Asian Cardiovasc Thorac Ann 2009; 87:1721 -1727.

36. Sajja LR, Mannam GC. Rare variants of internal thoracic artery in patients with coronary artery disease. Ind J ThoracCardiovasc. Surg 2009; 25: 68-70.

37. Mannam GC, Sajja LR, Dandu SBR, Pathuri SN, Saikiran KVSS, Sompalli S. Off-pump coronary revascularization for left main coronary artery stenosis.Asian CardiovascThorac .Ann. 2008; 16: 473-78.

38. Sajja LR, Koneti NR, Mannam GC,Kalyanasundaram M. Correction of anomalous drainage of right superior vena cava to left atrium. Asian Cardiovasc Thorac Ann 2008; 16: e32-4.

39. Sajja LR, Mannam GC,Gutti RS, Goli NR,Sompalli S, Penumatsa RR. Post infarction ventricular septal defect: repair by patch with infarct exclusion. Asian Cardiovasc Thorac Ann 2008; 16: 215- 220.

40. Sajja LR, Mannam GC, Dandu SBR, Pathuri SN, Saikiran KVSS, Sompalli S. Off – pump coronary artery bypass grafting in patients with significant left ventricular dysfunction. Ind J Thorac Cardiovasc. Surg, 2008; 24:110-115.

41. Sajja LR. Assessment of ulnar collateral circulation by the Allen test in patients undergoing radial artery harvest. Eur J Cardiothorac Surg 2008; 33:755.

42. Sajja, L.R., Mannam, G.C. Chakravarthi, R.M. In search of strategies for optimizing outcomes in patients with compromised renal function undergoing coronary artery bypass grafting. Cardiology 2008; 111:21-22.

43. Sajja LR, Mannam GC, Chakravarthi RM, Sompalli S, Naidu SK, Bhupathiraju S, Penumatsa RR. Coronary artery bypass grafting with or without cardiopulmonary bypass in patients with preoperative non-dialysis dependent renal insufficiency: A randomized study. J Thorac Cardiovasc Surg 2007; 133:378-88.

44. Sajja LR, Mannam GC. Angiographic patency of the radial artery conduit in coronary artery bypass grafting (Reply) Ann Thorac Surg. 2006; 81:1551-1552.

45. Sajja L R, Mannam G C, Sompalli S R, Simhadri C S R, Hasan A. Multinodular goiter compressing trachea following open heart surgery. Asian Cardiovasc Thorac Ann.2006;14: 416- 417.

46. Sajja L R, Mannam G C, Panthula N R, Sompalli S. The role of radial artery graft in coronary artery bypasses grafting. Ann Thorac Surg 2005:79: 2180-8.

47. Sajja LR, Mannam G, Sompalli S. Extrafacially harvested radial artery graft in CABG: Immediate arm complications and midterm clinical and angiographic results. J Card Surg 2005; 20:440-8.

48. Sajja LR, Mannam GC, Pantula NR, Sompalli S, Raju ARG, Raju BS. Reoperation for coronary artery disease in the young: early and mid-term results. (Ind J Thorac Cardiovasc. Surg, 2005:21:199-203).

49. Sajja L R, Mannam G C, Sompalli S, Reddy K V, Bala Raju S, Raju B S, Raju P K. Does multi vessel off-pump coronary artery bypass grafting reduce post-operative morbidity compared to on- pump CABG? Ind J Thorac Cardiovasc Surg 2004; 20:173-177.

50. Sajja L R, Mannam G, Sompalli S, Reddy K V, Raju R B, Anjaneyulu A V. Mid-term angiographic patency of radial artery graft: Does the site of proximal anastomosis effect the patency? Ind J Thorac Cardiovasc Surg 2004; 20:178-182.

51. Sajja L.R, Mannam GC. Right internal mammary artery and radial artery composite insitu pedicle graft in CABG. Ann Thorac Surg. 2002; 73:1856 – 1859.

52. Sajja LR, Mannam GC, Sompalli S. Neurologic hand complications after radial artery harvest for coronary bypass grafting. J Thorac Cardiovasc Surg. 2002;123:  585 – 586.

53. Sajja L.R., Mannam GC, Sompalli S. Is Allen’s test not reliable in selection of patients for radial artery harvest? Ann. Thorac Surg. 2002;74: 296

54. Sajja LR, Benjaram SR, Sahariah S, Devaraj VK. A giant aneurysm of renal artery: surgical management. Asian Cardiovasc Thorac Ann. 2002; 10:176 – 77.

55. L.R. Sajja, Mannam G.C. Role of closed mitral commissurotomy in mitral stenosis with severe pulmonary hypertension. J Heart Valve Dis 2001; 10:288-293.

56. Sajja L.R. Mannam G.C, Sompalli SR, Missula   SK, Accessory mitral valve tissue obstructing left ventricular outflow tract.  Asian Cardiovasc Thorac Ann. 2001; 9:325-6.

57. Mannam G.C, Sajja L.R., Yarlagadda R.B, Pothineni R.B, Repair of left ventricular outflow tract diverticulum in association with aortic stenosis. Ind J Thorac Cardiovasc Surg. 2001; 17: 90-92.

58. Sajja L.R. Mannam G.C, Krishnam Raju, S.Sompalli, R.S. Angajala. Right atrial myxoma arising from crista terminalis in septugenarian. Asian Cardiovasc Thorac Ann. 2001:9.322-4.

59. Sajja L.R., Mannam G.C, Alluri RGR, Sompalli SR. Off -pump coronary artery bypass grafting: a single centre experience Ind J Thorac Cardiovasc Surg. 2001; 17:77-81.

60. Sajja L.R, Farooqi A, Shaik M.S, Yarlagadda R.B, Baruah D.K, Pothineni R.B, Surgical revascularization in patients with dual left anterior descending coronary artery. Tex Heart inst J: 2000:27:292-6.

61. Sajja LR, Farooqi A, Yarlagadda R.B, Shaik M.S, Pothineni R.B, Retrograde coronary sinus perfusion for severe left main coronary artery stenosis. Asian Cardiovasc Thorac Ann 2000:8:290-1.

62. Sajja L.R, Farooqi. A, Yarlagadda R.B, Spontaneous dissection of left main coronary artery: surgical management. Asian Cardiovasc Thorac Ann 2000; 8: 54-5.

63. Sajja L.R, Kulshreshth P., Yarlagadda R.B, Continuous intravenous insulin infusion reduces infections in diabetics after CABG. Ann Thorac Surg 2000; 69: 667-68.

64. Sajja L.R, Farooqi A, Yarlagadda R.B, Shaik M.S, Surgical management of eventration of diaphragm in an elderly patient. Asian Cardiovasc Thorac Ann 2000; 8: 181-3.

65. Kulshreshtha P., L. Rao, Grab J.L., Rousou J.A., Englemen R.M, Wait R.B. use of extrafascially harvested radial artery for coronary artery revascularization: technical considerations. J Card Surg. 1999; 14: 26-31.

66. Sajja L.R., Rao S.P., Madhusudan KN, Naresh Kumar Reddy CR, Reddy BSR. Aorto-innominate vein fistula: a rare complication following open heart surgery Asian Cardiovascular Thorac Ann 1996:4:54-56.

67. Sampath Kumar A, Bhan A, Bajaj R, Lokeswara Rao S, P.Venugopal P, Srivastava S. Mitral Valve Repair : Techniques and Results. Indian Heart J: 1990:42:135-37.

68. E.V. Ussiri, GopiChand Mannam, Lokeswara Rao Sajja, J. Viswanath, D.S. Bhaskara Raju, S.Pathuri, S. Sompalli, N.K. Rao. Clinico-Surgical Outcome of Repair of Isolated Atrial Septal Defect at Care Hospital, Banjara Hills-Hyderabad India, 2004-2006. East and Central African Journal of Surgery 2007; 12:148-153.

69. Ussiri E.V, Nyawawa ETM, Mannam GC, Sajja LR, Bhaskara Raju DS, Pathuri SN, Saikiran KVSS, Sompalli S. Patterns of anomalous pulmonary venous connection as seen at Care Hospital, Hyderabad - India. East and Central African Journal of Surgery 2007; 12:18-22.

70. E.V. Ussiri, E.T.M. Nyawawa, U. Mpoki, E.R. Lugazia, G.C. Mannam, L.R. Sajja. S. Sompalli. Modified Blalock-Taussig Shunt in Palliative Cardiac Surgery. East and Central African Journal of Surgery 2007; 12:23-27.


 Published Discussions

                     

1.      Sajja LR Discussion of Fuster RG, Paredes F, Pelez AG, Martin E, C novas S, Gil O, et al. Impact of increasing degrees of renal impairment on outcomes of coronary artery bypass grafting: the off-pump advantage Eur J Cardio-Thorac Surg 2013 44:732-42. 

2.      Sajja LR. Discussion of Lemma MG, Coscioni E, Tritto FP, Centofanti P, Fondacone, Salica A, et al. On-pump versus off-pump coronary artery bypass surgery in high-risk patients: Operative vessels of a prospective randomized trial (on-off study). J Thorac Cardiovasc Surg 2012; 143:625-631.

3.      Sajja LR. Discussion of Glineur D,  Dhoore W,  de Kerchove L,  Noirhomme P,  Price J, Hanet C et al . Angiographic predictors of 3-year patency of bypass grafts implanted on the gastroepiploic artery, saphenous vein, and right internal thoracic artery grafts right coronary artery system: A prospective randomized comparison of gastroepiploic artery, saphenous vein, and right internal thoracic artery grafts. J Thorac Cardiovasc Surg.2011; 142:980-988.

4.      Sajja LR. Discussion of Elmistekawy E, Chan V , Bourke M E, Dupuis J-Y,. Rubens F D, Mesana T G and Ruel M. Off-pump coronary artery bypass grafting does not preserve renal function better than on-pump coronary artery bypass grafting: Results of a case-matched study. J ThoracCardiovascSurg2012;143:85-92

5.      Sajja LR. Discussion of Paone G et al. Preoperative predicted risk does not fully explain the association between red blood cell transfusion and mortality in coronary bypass surgery.J Thorac Cardiovasc Surg 2012; 143:184-185.

 

The list of the books where Dr. Sajja's work has been cited

 

1.     State of the Art Surgical Coronary Revascularization-Page 297

 


 avid P Taggart, John D Puskas2021

  • Sajja LR, Mannam G, Dandu SB, Sompalli S. Reduction of sternal wound infections in diabetic patients undergoing off-pump coronary artery bypass surgery and using modified pedicle bilateral internal thoracic artery harvest technique. J Thorac Cardiovasc Surg. 2012; 144(2):480-5. (Harvesting arterial conduits, Technical aspects of coronary artery bypass graft surgery)
  • Taggart DP, Gaudino MF, Gerry S, Gray A, Lees B, Sajja LR, et al. Ten-year outcomes after off-pump versus on-pump coronary artery bypass grafting: insights from the Arterial Revascularization Trial. J Thorac Cardiovasc Surg. 2020 Feb 19:S0022-5223(20)30427.

 

2.     Technical Aspects of Modern Coronary Artery Bypass Surgery-Page 184Mario Gaudino 2020

  • Sajja L.R. Strategies to reduce deep sterna wound infection after bilateral internal mammary artery grafting Int J Surg 2015; 16 (Pt B):171-8. (Techniques to avoid sternal complications after CABG with bilateral internal mammary artery)
  • Sajja LR, Mannam G. Internal thoracic artery: anatomical and biological characteristics revisited. Asian Cardiovasc Thorac Ann 2015; 23:88-99. (Bilateral internal thoracic artery grafting strategies, Techniques to avoid sternal complications after CABG with bilateral internal mammary artery)
  • Sajja LR, Mannam G, Dandu SBR, Sompalli S. Reduction of sternal wound infections in diabetic patients undergoing off-pump coronary artery bypass surgery using modified pedicle bilateral internal thoracic artery harvest technique. J Thorac Cardiovasc Surg 2012; 144(2):480-5. (Bilateral internal thoracic artery grafting strategies)

 

3.     Sabiston and Spencer Surgery of the Chest E-Book-Page 1601


            Frank SellkePedro J. del NidoScott J. Swanson 2015

  • Sajja L.R, Mannam G, Chakravarthi RM, Sompalli S, Naidu SK, Somaraju B et al. Coronary artery bypass grafting with or without cardiopulmonary bypass in patients with preoperative non-dialysis dependent renal insufficiency: a randomized study. J Thorac Cardiovasc Surg 2007; 133:378-388.

 

4.     Cardiac Surgery in the Adult, Third Edition

Lawrence H. Cohn 2007

  • Sajja LR, Mannam G., Pantula, NR., Sompalli S. Role of radial artery Y-graft in coronary artery bypass grafting. Ann Thorac Surg. 2005. 79(6):2180-8.

 

5.     Cardiac Surgery in the Adult, Fourth Edition

Lawrence H. Cohn 2012

Sajja et al. demonstrated that the use of cardiopulmonary bypass was significantly associated with an adverse renal outcome.

  • Sajja L.R, Mannam G, Chakravarthi RM, Sompalli S, Naidu SK, Somaraju B et al. Coronary artery bypass grafting with or without cardiopulmonary bypass in patients with preoperative non-dialysis dependent renal insufficiency: a randomized study. J Thorac Cardiovasc Surg 2007; 133:378-38.

6.     Cardiac Surgery in the Adult Fifth Edition-Page 536

Lawrence H. CohnDavid H. Adams 2017

  • Sajja L.R, Mannam G, Chakravarthi RM, Sompalli S, Naidu SK, Somaraju B et al. Coronary artery bypass grafting with or without cardiopulmonary bypass in patients with preoperative non-dialysis dependent renal insufficiency: a randomized study. J Thorac Cardiovasc Surg 2007; 133:378-388.

 

7.     Anatomic Exposures in Vascular Surgery-Page 215

Gary G. WindR. James Valentine 2013

  • Sajja LR, Mannam G., Pantula, N.R. and Sompalli S. 2005. Role radial artery graft in coronary artery bypass grafting. Ann Thorac Surg. 79(6): 2180-8.

 

 

8.     Arteri�ln� revaskularizace myokardu-Page 113

Gwozdziewicz Marek 2007

Language: Czech

  • Sajja LR, Mannam G., Pantula, NR., Sompalli S. Role of radial artery Y-graft in coronary artery bypass grafting. Ann Thorac Surg. 2005. 79(6):2180-8.

 

9.     Anesthetic and Obstetric Management of High-Risk Pregnancy

    Sanjay Datta.2006

  • Sajja LR, Mannam GC. Role of closed mitral commissurotomy in mitral stenosis with severe pulmonary hypertension. J Heart Valve Dis. 2001; 10(3):288-93.

 

10. Cardiac Surgery Essentials for Critical Care Nursing-Page 126

Sonya Hardin, ?Roberta Kaplow  2010

  • Sajja L.R, Mannam G., & Sompalli S, (2005). Extrafascially harvested radial artery in CABG: Technique of harvest, complications, and midterm angiographic patency. Journal of Cardiac Surgery, 20(5), 440-448.

 

 

11. Cardiac Surgery Essentials for Critical Care Nursing (Second Edition)-Page 97

Sonya Hardin, ?Roberta Kaplow

  • Sajja L.R. (2008). Assessment of ulnar collateral circulation by the Allen test in patients undergoing radial artery harvest. European Journal of Cardio-Thoracic Surgery, 33(4), 755-756.

 

 

12. Cardiac Regeneration and Repair- Biomaterials and Tissue Engineering

Richard D. Weisel 2014

  • Sajja LR, Mannam G., Pantula, N.R. and Sompalli S. 2005. Role radial artery graft in coronary artery bypass grafting. Ann Thorac Surg. 79(6): 2180-8.

 

13. Coronary Artery Bypass Grafting Surgery for Atherosclerotic Cardiac Disease-Page 72

Mehmet Erdem Toker 2021

A prospective randomized trial showed that ONCAB as compared with OPCAB was more deleterious to renal function in diabetic patients with non-dialysis-dependent renal insufficiency (Sajja et al. 2007).

  • Sajja L.R, Mannam G, Chakravarthi RM, Sompalli S, Naidu SK, Somaraju B et al. Coronary artery bypass grafting with or without cardiopulmonary bypass in patients with preoperative non-dialysis dependent renal insufficiency: a randomized study. J Thorac Cardiovasc Surg 2007; 133:378-388.

 

14. Coronary Artery Bypass Advances in Research and Application: 2012 Edition

Q. Ashton Acton, PhD 2012

  • Sajja and colleagues published their study in Annals of Thoracic Surgery (Impact of Preoperative Renal Dysfunction on Outcomes of off-pump Coronary Artery Bypass Grafting. Annals of Thoracic Surgery, 2011:92(6):2161-2167).

 

15. Coronary Graft Failure: State of the Art-Page 262

Aamer Abbas, Hironori Kitabata, Ion C. ?intoiu, Malcolm John Underwood, Stephane Pierre Cook

  • Sajja L.R, Mannam G., & Sompalli S, (2005). Extrafascially harvested radial artery in CABG: Technique of harvest, complications, and midterm angiographic patency. Journal of Cardiac Surgery, 20(5), 440-448.

16. Comprehensive Cardiovascular Medicine in the Primary Care Setting-Page 309

Christopher P. Cannon, Peter P. Toth 2018

  • Sajja L.R. Strategies to reduce deep sterna wound infection after bilateral internal mammary artery grafting Int J Surg 2015;16 (Pt B):171-8.

 

17. Conduits for Myocardial Revascularization

Michel CarrierL. Conrad Pelletier 1993

 

18. Cumulated Index Medicus (1991)-Page 6096 (1991)

 

  • Sajja LR, Kulshreshth P, Yarlagadda R.B. Continuous intravenous insulin infusion reduces infection in diabetics after CABG. Ann Thaorac Surg 2000; 69:667-68.

 

19. Cardiology E-Book-Page 1951

Michael H. CrawfordJohn P. DiMarcoWalter J. Paulus 2009

  • Sajja L.R, Mannam G, Chakravarthi RM, Sompalli S, Naidu SK, Somaraju B et al. Coronary artery bypass grafting with or without cardiopulmonary bypass in patients with preoperative non-dialysis dependent renal insufficiency: a randomized study. J Thorac Cardiovasc Surg 2007; 133:378-388.

 

 

 

20. Cardiovascular Imaging E-Book-Page 476

Vincent HoGautham P. Reddy 2010

  • Sajja LR, Farooqi A, Shaik MS, Yarlagadda RB, Baruah DK, Pothineni RB. (2000). Dual left anterior descending coronary artery: surgical revascularization in 4 patients. Tex Heart Inst J 27(3):292-296.

 

21. Ecocardiografia clinica

 Michael Y. HeneinMary SheppardJohn PepperMichael Rigby  2007

   Language: Italian

  • Sajja LR, Mannam GC. Role of closed mitral commissurotomy in mitral stenosis with severe pulmonary hypertension. J Heart Valve Dis. 2001; 10(3):288-93

22. Degenerative Aortic Valve Disease, Its Mechanism on Progression, Its Effect on the Left Ventricle and the Postoperative Results-Page 223

Wilhelm Peter Mistiaen 2013

  • Sajja L.R, Mannam G, Chakravarthi RM, Sompalli S, Naidu SK, Somaraju B et al. Coronary artery bypass grafting with or without cardiopulmonary bypass in patients with preoperative non-dialysis dependent renal insufficiency: a randomized study. J Thorac Cardiovasc Surg 2007; 133:378-388.

 

23. Indian Science Abstracts (Volume 44)-Page 95

Indian National Scientific Documentation Centre, Delhi 2008

  • Mannam G, Sajja LR, Raju B, Dandu S, Pathuri S N, Raju B S et al. Indian J Thorac Surg. 2007;23(1):88-9. (CARE Hospitals, the Institute of Medical Sciences, Hyderabad).

 

 

24. Implantable Defibrillator Therapy: A Clinical Guide-Page 109

Antonio PacificoGust H. BardyPhilip D. HenryMartin BorggrefeFrancis E. MarchlinskiAndrea NataleBruce L. Wilkoff � 2012

  • Sajja LR, Kulshresth P, Yarlagadda RB. Continuous insulin infusion reduces infection in diabetics after CABG. Ann Thorac Surg 2000; 69:667-668.

 

25. Manual of Perioperative Care in Adult Cardiac Surgery-Page 724

Robert M. Bojar 2020

  • Sajja L.R, Mannam G, Chakravarthi RM, Sompalli S, Naidu SK, Somaraju B et al. Coronary artery bypass grafting with or without cardiopulmonary bypass in patients with preoperative non-dialysis dependent renal insufficiency: a randomized study. J Thorac Cardiovasc Surg 2007; 133:378-388.

 

26. Medical Management of the Surgical Patient-Page 328

A Textbook of Perioperative Medicine 2013

Michael F. Lubin, Neil H. Winawer, Thomas F. Dodson

  • Sajja L.R, Mannam G, Chakravarthi RM, Sompalli S, Naidu SK, Somaraju B et al. Coronary artery bypass grafting with or without cardiopulmonary bypass in patients with preoperative non-dialysis dependent renal insufficiency: a randomized study. J Thorac Cardiovasc Surg 2007; 133:378-388.

 

27. Off-Pump Coronary Artery Bypass-Page 108

Hitoshi Yokoyama, Masami Ochi, Tohru Asai 2015

  • Sajja LR, Mannam G (2002) Right internal mammary artery and radial artery composite in situ pedicle graft in coronary artery bypass grafting. Ann Thorac Surg 73:1856-1859.

 

28. Off-Pump Coronary Artery Bypass Grafting- Outcomes, Concerns and Controversies

Mohamed Amrani, Shahzad G. Raja 2012

 

 

29. Oxford Textbook of Clinical Nephrology-Page 1903

Neil Turner 2015

Since many of the recent trials were not yet published at time of writing the guidelines, the KDIGO Work Group concluded that there was not enough evidence to recommend off-pump coronary artery bypass for reducing AKI or the need for RRT (Kidney Disease: Improving Global Outcomes (KDIGO) Acute Kidney Injury Work Group, 2012). Based on the study by Sajja et al. (2007), this opinion should probably be modified for patients with advanced CKD.

  • Sajja L.R, Mannam G, Chakravarthi RM, Sompalli S, Naidu SK, Somaraju B et al. Coronary artery bypass grafting with or without cardiopulmonary bypass in patients with preoperative non-dialysis dependent renal insufficiency: a randomized study. J Thorac Cardiovasc Surg 2007; 133:378-388.

 

 

30. Perioperative Kidney Injury-Principles of Risk Assessment, Diagnosis and Treatment-Page 79

Charuhas V. Thakar, Chirag R. Parikh 2014

  • Sajja L.R, Mannam G, Chakravarthi RM, Sompalli S, Naidu SK, Somaraju B et al. Coronary artery bypass grafting with or without cardiopulmonary bypass in patients with preoperative non-dialysis dependent renal insufficiency: a randomized study. J Thorac Cardiovasc Surg 2007; 133:378-388.

 

31. Revisiting Cardiac Anatomy: A Computed-Tomography-Based Atlas and Reference

Farhood Saremi � 2011

  • Sajja LR, Farooqi A, Shaik MS, Yarlagadda RB, Baruah DK, Pothineni RB. (2000). Dual left anterior descending coronary artery: surgical revascularization in 4 patients. Tex Heart Inst J 27(3):292-296.

 

32. Special Topics in Cardiac Surgery-Page 24

Cuneyt Narin 2012

  • Sajja L.R, Mannam G, Chakravarthi RM, Sompalli S, Naidu SK, Somaraju B et al. Coronary artery bypass grafting with or without cardiopulmonary bypass in patients with preoperative non-dialysis dependent renal insufficiency: a randomized study. J Thorac Cardiovasc Surg 2007; 133:378-388.

 

33. The Complete Guide to Cardiac CT-Page 324

Simeon Abramson 2011

  • Sajja LR, Mannam G., Pantula, N.R. and Sompalli S. 2005. Role radial artery grafts in coronary artery bypass grafting. Ann Thorac Surg. 79(6): 2180-8.

34.  CSI Textbook of Cardiology: The Indian Perspective

 

 

Editor-in-Chief: Pradip K Deb

  • Sajja LR, Beri P. Bilateral internal thoracic artery grafting in India: Time to raise the bar. Indian Heart J. 2017; 69:640-5.
  • Sajja L.R, Mannam G, Chakravarthi RM, Sompalli S, Naidu SK, Somaraju B et al. Coronary artery bypass grafting with or without cardiopulmonary bypass in patients with preoperative non-dialysis dependent renal insufficiency: a randomized study. J Thorac Cardiovasc Surg 2007; 133:378-388.
  • Mannam G, Sajja LR, Dandu SB, et al. Off-pump coronary revascularization for left main coronary artery stenosis. Asian Cardiovasc Thorac Ann. 2008; 16: 473-8.
  • Sajja LR, Yarlagadda RB, Shaik MS, et al. Retrograde coronary sinus perfusion for severe left main stenosis. Asian Cardiovasc Thorac Ann. 2000; 8:290-1.
  • Sajja LR, Mannam G, Dandu SB, et al. Analysis of thirty-day outcomes of off-pump versus on-pump coronary artery bypass grafting: A large cohort study. Interact CardiVasc Thorac Surg. 2012; 15(Suppl2): i-xxvii.
  •  Sajja LR, Mannam G, Dandu SB, et al. Reduction of sterna wound infections in diabetic undergoing off-pump coronary artery bypass surgery and using modified pedicle bilateral internal thoracic artery harvest technique. J Thorac Cardiovasc Surg. 2012; 144:480-5.
  • Sajja LR, Mannam G, Sompalli S. Extrafascially harvested radial artery in CABG: Technique of harvest, complications and mid-term angiographic patency. J Card Surg. 2005;20:440-8
  • Sajja LR, Mannam G. Right internal mammary artery and radial artery composite in situ pedicle graft in coronary artery bypass grafting. Ann Thorac Surg. 2002;73:1856-9.
  • Sajja LR, Mannam GC, Gutti RS, et al. Post infarction ventricular septal defect: Repair by patch with infarct exclusion. Asian Cardiovasc Surg Ann. 2008; 16:215-20.
  • Sajja LR, Mannam GC, Dandu SBR, et al. Outcomes of mitral valve repair for chronic ischemic mitral regurgitation. Asian Cardiovasc Surg Ann. 2009; 87:1721-7.

 

35. Deep Sternal wound Infections

Raymund E. Horch, ?Christian Willy, ?Ingo Kutschka 2017

 

36.  Clinical Ecocardiography

Michael Y. Henein 2012

  • Sajja LR, Mannam GC. Role of closed mitral commissurotomy in mitral stenosis with severe pulmonary hypertension. J Heart Valve Dis. 2001; 10(3):288-93

 

37.  Master Techniques in  Surgery

Frederick Grover, ?Michael J. Mack 2016 

 

38.  Multimodal Cardiovascular Imaging: Principles and Clinical Applications

Olle Pahlm, ?Galen S. Wagner 2011

  • Sajja LR, Farooqi A, Shaik MS, Yarlagadda RB, Baruah DK, Pothineni RB. (2000). Dual left anterior descending coronary artery: surgical revascularization in 4 patients. Tex Heart Inst J 27(3):292-296.

 

39.  STS Cardio thoracic Surgery E-Book

  • Sajja L.R, Mannam G, Chakravarthi RM, Sompalli S, Naidu SK, Somaraju B et al. Coronary artery bypass grafting with or without cardiopulmonary bypass in patients with preoperative non-dialysis dependent renal insufficiency: a randomized study. J Thorac Cardiovasc Surg 2007; 133:378-388.

40.  Sabiston & Spencer Surgery of the Chest - Volume 2

 

 

Frank W. Sellke 2005

 

 

 

 

 

* Introduction of New Heart Surgery

*He is the Founder-President of the Society of Coronary Surgeons, which was inaugurated virtually by His Excellency Honorable Vice-President of India Shri M. Venkaiah Naidu Ji in December 2020.

* He is elected as the Junior Vice-President of IACTS during the 67th Annual Conference of the Indian Association of Cardiovascular-Thoracic Surgeons (IACTS) held between 26 and 28th Feb 2021. He shall be installed as the President of IACTS in 2023.

* Promote Patency Trial; the first multi-centric Randomized Controlled trial conducted in Cardiac Surgery in India by seven Cardiac Surgeons under the leadership of Dr. Lokeswara Rao Sajja was published in the Indian Journal of Thoracic Cardiovascular Surgery was selected for the Best Original Article 2020 award during the 67th Annual Conference of IACTS.

* Dr. Sajja is one of the Authors of a paper published from the Arterial Revascularization Trial, one of the largest and longest followed-up multi-national RCT in Cardiac Surgery, -Ten-year outcomes after off-pump versus on-pump coronary artery bypass grafting: Insights from the Arterial Revascularization Trial, was published in The Journal of Thoracic and Cardiovascular Surgery-2020.

* He Presented contemporary trends in coronary artery surgery in India at the old Congress on cardia sciences in 2018

* The study was presented at the Annual Meeting of the American for Thoracic Surgery at SanDiego in April-2008

* PROMOTE Patency- Prospective Randomized comparison of Off-pump and On-pump Multivessel cOronary artery bypass surgery To Evaluate outcomes and graft patency. The study was conducted at 6 centers in India (Hyderabad, Kolkata, Mumbai, Nadiad, Coimbatore) a total of 320 patients were enrolled.

* Dr. Sajja delivered a lecture in Dr. C Sambasiva Rao Memorial Endowment CME program on Recent advances in Cardiac Surgery at Guntur Medical College, Guntur on 28.Feb.2016.

* Lokeswara Rao Sajja. Bilateral internal thoracic artery grafting in India - time to raise the bar. Presented at American Association for Thoracic Surgery International Coronary Congress held in New York, USA. August 21-23,2015.

* Lokeswara Rao Sajja, Gopi Chand Mannam , Rama Chandra Raju Pusapati Ramesh Gudapati, Raghava Raju Penumatsa Jyothsna Guttikonda Sriramulu Sompalli. Analysis of thirty-day outcomes of off-pump versus on-pump coronary artery bypass grafting: a large cohort study. Presented at American Association for Thoracic Surgery International Coronary Congress held in New York, USA. August 21-23,2015.

* Sajja LR, Strategies to reduce deep sternal wound infection after bilateral internal mammary artery grafting. Int J Surg. 2015;16: 171-178.

* Lokeswara Rao Sajja. The Journey of Surgery for Coronary Artery Disease in India: Adoption, Customization and Innovation. Sadasivan Oration. Indian J Thorac Cardiovasc Surg. 2014; 30:116-128.

Healthy Heart Ride 2014 - KBR Park Hyderabad









Lokeswara Rao Sajja. The journey of surgery for coronary artery disease in India: adoption, customization and innovation. Sadasivan Oration of Indian Association of Cardiovascular Thoracic Surgeons June 2014, Volume 30, Issue 2, pp 116-128

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